A groundbreaking analysis of data from the Adolescent Brain Cognitive Development (ABCD) Study has revealed significant sleep disparities among transgender early adolescents, highlighting a critical area of concern for youth well-being and health. The study, which examined caregiver-reported sleep outcomes in a large national cohort, found that transgender youth aged 12-13 years were substantially more likely to experience sleep disturbances, insomnia symptoms, excessive daytime sleepiness, and shorter sleep durations compared to their cisgender peers. These findings underscore the urgent need for targeted screening and intervention strategies to address the unique challenges faced by this vulnerable population.
The Critical Role of Sleep in Adolescent Development
Sleep is not merely a period of rest; it is a fundamental biological process that underpins virtually every aspect of adolescent development. During these crucial formative years, adequate and quality sleep is essential for physical growth, brain maturation, cognitive function, emotional regulation, and the consolidation of learning. Disruptions to sleep patterns in early adolescence can have far-reaching consequences, contributing to a cascade of negative health outcomes.
Research consistently links poor sleep in adolescents to an increased risk of obesity, metabolic disorders, and weakened immune systems. Cognitively, insufficient sleep can impair attention, memory, problem-solving abilities, and academic performance, potentially hindering educational attainment. Emotionally, sleep deprivation is a significant risk factor for the development or exacerbation of mental health conditions, including depression, anxiety, and irritability. Furthermore, poor sleep has been associated with increased impulsivity and a greater propensity for engaging in risky behaviors, such as substance use and unsafe sexual practices.
Unveiling Sleep Disparities in Transgender Youth
While previous research has documented sleep challenges within other marginalized adolescent groups, such as sexual minority youth, the specific sleep experiences of transgender and gender diverse adolescents have remained largely under-explored. The ABCD Study’s recent analysis fills this critical knowledge gap, providing robust evidence of significant sleep inequities faced by transgender youth.
The study, a cross-sectional analysis of Year 3 data collected between 2019 and 2021, involved a diverse cohort of 10,277 adolescents aged 12 to 13 years from 21 participating sites across the United States. Of this cohort, approximately 1% identified as transgender. The researchers utilized the validated Sleep Disturbance Scale for Children (SDSC) to gather caregiver-reported data on various sleep parameters. Statistical models were employed to evaluate the associations between transgender identity and sleep measures, controlling for potential confounding factors.
Key Findings: A Stark Picture of Sleep Disturbance
The results painted a clear and concerning picture: caregivers of transgender adolescents reported significantly higher rates of overall sleep disturbance compared to caregivers of cisgender youth. This elevated risk was quantified by an adjusted relative risk (RR) of 2.15 (95% Confidence Interval [CI], 1.52–3.04; p < 0.001), indicating that transgender adolescents were more than twice as likely to experience sleep disturbances. Notably, adolescents who responded "maybe" to the transgender identity question also showed similar trends, suggesting that even the process of questioning one’s gender identity may be associated with sleep challenges.
Further detailed analysis of specific sleep subscales revealed the multifaceted nature of these disparities. Transgender adolescents were found to have significantly higher rates of disorders related to initiating and maintaining sleep, a category encompassing difficulties falling asleep and staying asleep. This points towards a potential struggle with insomnia symptoms that is more prevalent in this group.
Perhaps one of the most striking findings was the reported shorter sleep duration among transgender youth. Across nearly all sleep categories, caregivers reported that transgender adolescents obtained less sleep on average. When compared to the recommended range of nine to 11 hours of sleep for this age group, transgender adolescents were significantly more likely to report sleeping:
- Eight to nine hours per night
- Seven to eight hours per night
- Five to seven hours per night
- Fewer than five hours per night
The disparity was particularly pronounced in the most severe category of sleep deprivation. Transgender adolescents exhibited a dramatically increased likelihood of sleeping fewer than five hours per night, with an adjusted RR of 38.97 (95% CI, 2.78–545.73; p = 0.007). This indicates an alarmingly high risk of severe chronic sleep deprivation within this subgroup.
Potential Contributing Factors: Minority Stress and Beyond
The authors of the study propose several interconnected factors that may contribute to these observed sleep disparities. A primary consideration is the concept of "minority stress." This framework posits that individuals belonging to marginalized groups experience chronic stress arising from societal prejudice, discrimination, and stigma. For transgender adolescents, this can manifest in various forms, including:
- Gender Dysphoria: The distress experienced when one’s gender identity does not align with their sex assigned at birth. This internal conflict can lead to significant psychological distress, anxiety, and depression, all of which are known to disrupt sleep.
- Psychosocial Distress: The cumulative impact of navigating a world that may not affirm their identity can lead to increased levels of anxiety, depression, and feelings of isolation. These emotional states are powerful inhibitors of restful sleep.
- Social Stigma and Discrimination: Transgender youth often face bullying, rejection from peers and family, and systemic discrimination in various aspects of their lives, from school to healthcare. This constant exposure to negative social interactions and environments can profoundly impact mental well-being and sleep quality.
- Lack of Social Support: Inadequate or unsupportive family, peer, or school environments can exacerbate the stress experienced by transgender youth, leaving them without crucial protective factors that promote resilience and well-being.
The study also acknowledges that adolescents who are questioning their gender identity may experience similar stressors. The uncertainty, internal conflict, and potential for societal disapproval associated with exploring one’s gender can create a climate of stress that similarly disrupts sleep patterns.
Limitations and Future Directions
While the ABCD Study’s findings are significant, the researchers are candid about the study’s limitations. The reliance on caregiver-reported sleep data, while common in pediatric research, introduces a degree of subjectivity and potential for recall bias. Furthermore, the number of transgender participants, though representing approximately 1% of the cohort, is relatively small, which can limit the statistical power for some analyses. The study also acknowledges the lack of more nuanced gender identity categories beyond "transgender" and "cisgender," which could provide a more detailed understanding of the spectrum of experiences. Finally, the cross-sectional design of the study means that causal inferences cannot be definitively drawn; it establishes an association rather than proving that transgender identity directly causes sleep disturbances.
Despite these limitations, the study represents a critical step forward in understanding the health needs of transgender adolescents. It is one of the first large-scale national analyses to systematically demonstrate significant sleep disparities in this population.
Broader Impact and Implications for Healthcare
The implications of these findings are profound and far-reaching, particularly for healthcare providers, educators, and policymakers. The identified sleep disparities suggest that transgender early adolescents are at an elevated risk for a range of health problems associated with poor sleep. This underscores the imperative for proactive and inclusive healthcare practices.
Clinical Relevance: Healthcare providers working with adolescents should consider incorporating routine screening for sleep disturbances in all young patients, with a particular focus on transgender and gender questioning youth. This screening should be sensitive and affirming, creating a safe space for adolescents to discuss their experiences. Understanding these sleep issues can inform more comprehensive care plans that address both the physical and mental health needs of transgender youth.
Intervention Strategies: The findings strongly support the development and implementation of targeted interventions aimed at improving sleep hygiene and addressing the underlying stressors contributing to sleep disturbance. These interventions might include:
- Psychoeducation: Educating adolescents and their caregivers about the importance of sleep and strategies for improving sleep hygiene.
- Cognitive Behavioral Therapy for Insomnia (CBT-I): Adapting evidence-based therapies for insomnia to be culturally competent and responsive to the unique needs of transgender youth.
- Stress Management and Resilience Building: Providing tools and support for managing minority stress, building coping mechanisms, and fostering resilience.
- Family and Social Support Enhancement: Encouraging supportive family environments and facilitating access to affirming peer groups and community resources.
Policy and Advocacy: The study’s results can serve as a powerful advocacy tool to highlight the health inequities faced by transgender youth. Policymakers and public health organizations should consider how to best support initiatives that promote the well-being of transgender adolescents, including access to gender-affirming care and comprehensive mental health services that recognize the interconnectedness of gender identity, mental health, and physical health.
Future Research: The study’s limitations also point towards crucial areas for future research. Longitudinal studies are needed to track the development of sleep patterns in transgender adolescents over time and to explore the causal pathways between gender identity, minority stress, and sleep outcomes. Further research should also aim to include more diverse gender identity categories and to gather data directly from transgender adolescents themselves, in addition to caregiver reports. Investigating the impact of gender-affirming care on sleep outcomes would also be a valuable area of inquiry.
In conclusion, the ABCD Study’s findings serve as a critical wake-up call. The significant sleep disparities identified in transgender early adolescents demand attention and action. By acknowledging and addressing these challenges, we can move towards a future where all adolescents, regardless of their gender identity, have the opportunity to achieve healthy sleep and, consequently, thrive.
Citation: Ricklefs C, et al. Gender identity disparities in early adolescent sleep: findings from the Adolescent Brain Cognitive Development Study. LGBT Health. 2025;12:231-236. doi:10.1089/lgbt.2023.0431.

